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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2843aaa911297189dbf371c5ec7bfed2ce67f7eb18b1b2188464b2e2b4497b95' 
  AND token = 'oCK+cdWw1+RI+e+GXsJe9fNa0WlkadInbTv37kA8LZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}