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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cb423e3deb07cb65b3153aee6d92f51841552e15305f0487e41a546b9e74c6c' 
  AND token = 'W5mRE9uAtIqXSy3eEI8X0W1k5bD+beS/yTTb9Pd23n4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}