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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3a7f281ceb58a08a0f6d7f0f42a1af8fa49504770d4dbb986eca3445bc50d9e' 
  AND token = '29e1vyC+NlNkdw22RyChrijAdTqlvGxn24ibR8U3Xvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}