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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8427bdf7d7f4faf6e78ab3ed43a24bde78d7bd579f86045358fab72543aede08' 
  AND token = 'GTa+lDAOKR5XMHbivAG0fPwfz1o0OSSmvNO+xNQbaZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}