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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d3c433c2778bb6f46a79e49fe91a86cb0674feb55ab51cdc7e1d83504405afa' 
  AND token = 'g3nutWTMDLPDutJlEmIQPEzOPe/prwXjLaNW60DEpwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}