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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'addf7b80390d164469e6369e176f743e26e333f7699f7ffc71a12f92b004cdda' 
  AND token = 'GqwS2UF5atQiVsmncTc7PGkz1eTha2RpTFqBSpGUACI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}