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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d64bc7af30e46ee4d40e220673bb804852780da098be87501e90f707af736a0' 
  AND token = 'cyEIH1wlww1MqU+9VOpqIgjKaQVxK0gi79UKd35rDAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}