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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4016c10a2c68f89a6c1d4e6f706c8ac25155bb9ba24b902de5e645cead09846' 
  AND token = 'wArpKcS0ES8SQWme2zM5vtDxfv3cm890bkJWIvEasyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}