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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1b066d1643ebf277d9d3f9550e50ad5b7fe993ca75e0c2047fd000628439d24' 
  AND token = 'ba9IUm3RgXZnIUOCGhkPiG/I++jYh0Coa6Qh5X+2p7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}