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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '728637d2600a109ced5a6f790f7476ac8c334f5e91298ce625d2203f0e506614' 
  AND token = 'wvtzc6YyOl/VsaCFlOPXWqL1/5sbwhMYvjkc4IjR0rc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}