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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c72e5bfb4fd909dd3aa7f00211e6f32647fbec40af1f4b0142d1b4682b9a7599' 
  AND token = 'NqZ+IW6rxsrMvqA8dVPEsPsFxVUeuY33kTkwJyBe2e4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}