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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49833259bbc27b08cc1d838c52755bf776ceda60c67e170c09b8497beffc424b' 
  AND token = 'nhr28lfFLabApNqBg5+01Rn2znO2c9uwJlrtRs/tsFo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}