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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80297d27ca2a3b8b78d4ec19871b46a24f11faa5a2263a1ffd4d03e2cd3adf7b' 
  AND token = 'HjlO1NHsYDckQnQtU773Nn4tHGaAjCTdXoU1EbkS9BA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}