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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a48e5676f55bd624f71a68e9e5fe4898af18b5ed82a7889fae335c94f087a5af' 
  AND token = 'Drgk4DWh5IcQVbMNmD+2QWVgldd2MiwiHo2NlDuRnHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}