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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44690b30e5296b0ee0e0d0d39ab082d68adeb38d9faf4ff0feee2ee2c1273e37' 
  AND token = 'w2MlMtZ9vAGGIEoICoNh/LBZZjf6NcOgacVv2gaP7ls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}