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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c48681b3202a3dcec2a8ffa73ab80b11816302e6302ced3325af0dbac70b589' 
  AND token = 'fFQ4jU5f/RnlpwNcMmYeI7jUJ+8byCRZGT1ZS/HDbJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}