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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85b2306556f332b8db998f5a95a8b59d1bac564b5a905a2b984144be0d647760' 
  AND token = 'ChyHA6RVCDS0WDDmceIuLCiuBCTO/oMJKmrn+zdJ4SU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}