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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cdd67bb6337304be9e23ab98e4b7ca2013c1d1da260206cde98a540b0eaf0a0' 
  AND token = 'XvNzNS4cdEc16b6wnQFNTSLDKRYnUU6Lm2m32UmZ7RU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}