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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '608f2cbe0b444c7cbbb85f2822bfec83e3459d7c66b3868914e288f784cb12ae' 
  AND token = 'D5j6hDrU+Bcq80l5+UwbUjAtxFyGDy0mWbUPyOlKwZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}