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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53aa76476b8bf2a612cec9bd9512d3a978d8d8116b9c5d347e626d73002498cb' 
  AND token = 'vPKc0mutQdq3KHv/n4G8F6WvR4i/aRFFI8XPp2MrvaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}