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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2798a62f8405d47597d4a1e49f45f5448a56215b4b5bd0136312e455b9e2218a' 
  AND token = 'fyUVt4m/5AMf5ZofQBpm/W0xG7u0agU5blY960PaCt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}