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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '339c0bc821a0e8cfd0ac77b15b3203ddb76019662b9a65e8925c39b44028f888' 
  AND token = 'osTWNJ76w5maYDqZ63V0YXvf/V0d5OUuVrhF2tNZd/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}