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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fcb71b8d1e78a90b099aa76d3dd1a363e87d9247694562d98400e6303d97227c' 
  AND token = 'rCSQ/2XBNZ/ME2xN8VK87SnV07b/nLPrha8BRqsMAxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}