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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea9f84149eea407cd2439649fa66f9c667134be04494527f4c3682e89a03ca78' 
  AND token = 'bSvZaSYhRQxQ2RBm/34k7TmK61Q7NQL1Nq0Ol33uIFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}