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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22b9b6c6de3fece01f8fb471ef9518df7968c11b6a6c110acdc12efb1f6780c1' 
  AND token = 'acVPocULfW30XvqK5Rdq64pMpt7Gojlyzz6gamW5oCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}