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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '201005202703505270ef14430df5a1766956e7788de272339b8b93065c17204c' 
  AND token = 'GrXD433f9/upxDF8b6zIjru1ArupASxUDg93Vt04JiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}