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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d65c546e77b434cd2e97e6cc8a9cb4f221134c0a1897f9f255bf2423d58d8ca' 
  AND token = 'yEC0IfWOWypdnfII5B7okQWyZQqRmg0GLYWz4TQ800o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}