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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6729813b674d8570791ccdb5bac755f844c8d20e1c277eddbe1da060f7874c74' 
  AND token = 'uO3u7KNa81GA1IOeU/wwjusDr0w6H8Jl+E9IK1ZnGDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}