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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d45ef3253c3e2ce6f432c04cc11c1bacfea1eeabae05df890caeb13b692ff79' 
  AND token = 'zlyA/SnRhcT4GBbarNy6SGJQ0fgTHJ7LzHVB5E8VYDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}