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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76322fb73cc96509c4a04ab75f71a313cd653ce2f030d2cba92fdeac7a0d780b' 
  AND token = 'OV1s/IcVCKvKVyTZimnvtjfT1nA3nRDYKqD7L8783ZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}