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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '510e16d4fac50bbc243648d16d686ab68c3c1247fd3ed1624b7ee441f3ec9e64' 
  AND token = '1eFmo/DRHZKGgm2/KAgvKcjq7EmDoN+IbMgy7FR03e0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}