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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1e0bc2e9505f6559d20ce0d3a09612c06044a5b648039a0fe6f544eb034a46e' 
  AND token = '2SMaPX9jcAVS2lpvlfeAE1haAgFVhMrRWBhYjvHLRz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}