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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed536133177bbbfca2c0fed8734c43e342a389561d242a16158e2ec604cc11c4' 
  AND token = 'HfHl8ub2xiuRS1mpeEcM8S/fj77GWqVT1ZWiF/ruzT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}