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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b72d715bb0bf32dae8bb4f70a28f6f450c2aeb47305f50625c46c0a49fa662e' 
  AND token = 'KRDLpk9Y0mRRU9G+oCmBOYFlENdcNjlJXSvFRrcV4mo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}