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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2eaeb71c5fdb46cded874b0b0f250200a989a7703e7a2f1197b3344485ffc4b6' 
  AND token = 'M3VS3tpFfBobIrd0ttNeYFlwfsGoeBMyEmx8ho/r4N4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}