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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df1fa52a1c9582e9cdf2893e6b4ad50c8653b7c5c9af748886391b8d0007d42d' 
  AND token = 'nHPxKI0tGG8tAkS6CiYapgRObDZxLbNwt8nrtwX07+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}