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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34a71fc7cae243b2739a14252cb7d43bac4b79379278892b557667e60d045eb5' 
  AND token = 's1a3FdTBoix+5Py/Wong7bTf2WcsEntEPXJMlZOJG14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}