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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f97f51d0923f099168d80eb5c216775791afda1a1fd0457ce2e9d75e37dd66e' 
  AND token = 'rS5SOCAAowfuhfs06owCuaaChsh6sERYV6RMAKhms0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}