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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '154accad9ea4e4d238b90e36b8b19c1f4e97bcfdfd528f7a42b8415597636a1b' 
  AND token = 'etRkZrpCrmC28sx00PwjbbSlA8vqBdrVxC2ocMM+n1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}