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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb59c74f6d3eb452a3fb057db9d7d35fa2d74493c70704c895fb491d21aa88db' 
  AND token = 'EuV7B/oOnUmgNEm9EhuXWZiupYRZgD53oqmmIgQ4drQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}