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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2235fa3305a3e10edd47aef3870334029c1ebfb4410f8037704ccccb33e1942a' 
  AND token = 'CR16LaJnRj8kh2DFWduRPGNBRnTwq94nvqQV/5Gjmqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}