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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6336fe443ff2b4fdeccef3716d6c4e78e806cdc0152ca3e7f901d487de42f252' 
  AND token = 'Pxuu1ZVWetpkQJQfvoMVmkArIESmbn5pKLEo1HE3f14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}