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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce7d8e6951d68e036957991f2418019acdf61442287b7322c6b9e441710f6396' 
  AND token = 'D4TpOsp6OwdxlxAm9HTDKOFgUHs3te9EOmRqxUAq3RI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}