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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24db1264293215d16a1d55586712000df99e47e363311b36cb09325ade296d7e' 
  AND token = 'U/Yov23hlzk7lbrL9LneU6tjrVzW+EtdFSz2D+xlMHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}