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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac3f339d79ede9f9d2bbece2b0688507b3af7ba35e295de717e491f35a06b727' 
  AND token = 'fbOh42zamrSXtE4GRbHnK3INiJWb0MYRVsyHHGvPiCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}