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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdf1583b0f2f0ef1c575e2012ba09527c33716c7854e851083c4732c9ebd6f5b' 
  AND token = 'uZzT+jM0rDy7vL5W52cinRbwG3z37fnYjSbFeyyqqY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}