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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b715229b48658ce10e57469a42e60678a2fad25d10b0857532fa5e21d6d72284' 
  AND token = 'W3LvOd2+gF0qHmerxrrUICesmbeqh0/d5MhJbguIUbA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}