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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ea3a1bb850114bfeeb64e01679363b1771485b1a2b048538e799c97e1c59af7' 
  AND token = 'Md7Mz8FAcRkuD77hmb82kSNUPo/quWJ8aLLHgKQE4zw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}