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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1f00fb7f4454773d953bcc8a8355e21557b600e56e66991446ff4247f259464' 
  AND token = 'b2UVMQ6LU0Y7YicH7TeeMnLM7xn953UTYTQ6eDif38E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}