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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb805cee145706c1dbdf3e9b2fb527c1191b2cbdbd7b5df800607312c4c9d19a' 
  AND token = 'nn4rpFpEQYiYiwBsu9aZBwhjkSZeC0FxNUrE+EEsWG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}